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JCO Oncol Pract 19(5):278283 Chen C-H, Huang C-Y, Lin H-YH, Wang M-C, Chang C-Y, Cheng Y-F (2021) Association of sodium thiosulfate with risk of ototoxic effects from platinum-based chemotherapy: a systematic review and meta-analysis

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CRISPR-Cas9 whole genome-wide gene-knockout screens for suppressors and enhancers of C9orf72 DPRs in human cells revealed TMX2 as an important protective modifier against toxicity (Kramer et al., 2018)

In addition, aggregation as a result of the solubilization step is a common problem, resulting in false positives (Szidonya et al., 2008)

At present, most of the studies on the relationship between selenium and cancer are observational studies