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[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Garcia-Layana A., Recalde S., Hernandez M., Abraldes M.J., Nascimento J., Hernandez-Galilea E., Olmedilla-Alonso B., Escobar-Barranco J.J., Zapata M.A., Silva R., et al

Previous studies have reported that PKM2 is enzymatically active toward pyruvate only as a tetramer and acts as a transcription factor coactivator when tetrameric PKM2 dissociates into a dimer 28,29

doi: 10.1016/j.theriogenology.2017.01.026 167 KatagiriS.MoriyoshiM.TakahashiY

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Topical GHK-Cu is generally considered well tolerated for many individuals, though irritation and sensitivity may occur