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Yagoda N, von Rechenberg M, Zaganjor E et al (2007) RASRAFMEK-dependent oxidative cell death involving voltage-dependent anion channels

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We observed that glutarate can react with the thiols of lipoate, thereby blocking the enzymatic activity of PDHc 9

Hann HW, Stahlhut MW, Blumberg BS

Thus, through high consumption of NAD + , CD38 also indirectly impacts the activity of other NAD + -consuming enzymes such as sirtuins 52
