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Notably, microbiota-targeted precision therapies have been shown to significantly improve social deficits in ASD mouse models

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Additionally, SIRT1 inhibits alcohol-mediated inflammation through the NF-B pathway and decreases the expression of fibroblast markers, thereby alleviating liver fibrosis (Liu et al., 2022)

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Medchemcomm 10 , 18031809 (2019)

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Conversely, in placebo subgroup of patients with severe vasculogenic ED, no significant changes were detected in any of the assessed outcome measures

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