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The researchers used Annexin-V FACS analysis and DNA laddering to demonstrate that Sag activated apoptosis in the sensitive cell lines in a dose- and time-dependent manner

The pharmacokinetics of GSH, GSSG, and total GSH were characterized by the peak plasma concentration ( C max ), elimination half time ( t 1/2 ), and the area under the plasma concentration-time curve (AUC) for the first 60 min (BA Calc 2002, KFDA, Ver 1.1.1)

To block protein thiols, methanol-fixed ECs were incubated with 200 mM iodoacetamide in 100 mM Tris (pH 8.3) and 5 mM EDTA at 37 C for 1 h

Chemiosmotic coupling in oxidative and photosynthetic phosphorylation, Biol Rev Camb Philos Soc 1966;41(3): 445-502

The studies currently available on the use of both oral and parenteral GSH are promising but represent only pilot studies for the time being