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In addition, ferroptosis, as a form of inflammatory cell death, is associated with the release of DAMPs, which can trigger the innate immune system and activate the NF-B pathway through AGER [95, 109]

211 Astrocytes also protect the brain tissue through reactive astrogliosis

Collectively, these findings suggest that adult WT mice exhibit greater resilience to stress compared to their adolescent counterparts, whereas aberrant anxiety susceptibility in KI mice emerges selectively during adulthoodpotentially due to the aberrant increase in CCK expression in the mPFC that occurs only in adulthood

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