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These studies have used various animal models, including rats with Dahlia sensitivity, rats with spontaneous hypertension, rats with oppressiveness-ii indexed hypertension, and mice treated with Deoxycorticosterone Acetate (DOCA) Salt (Verhaar et al., 2020)

4,11,15 Inflammatory responses mediated by proinflammatory cytokines and pathways, such as nuclear factor kappa B (NF-B) and Toll-like receptor 4 (TLR4), worsen the condition by amplifying oxidative stress and hindering neuronal repair

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