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Recently, the regulation of ZIP10 expression by STAT3 and STAT5 was revealed and associated with suppression of apoptosis in human B cell lymphoma, suggesting some effects of homeostatic zinc signals on the development and survival of B cells

The importance of targeting glutathione levels is relevant because significant differences in glutathione and its related metabolites have been found in plasma (16, 17), white blood cells (58, 59), and post-mortem brains (11, 21) of participants with ASD

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Consequences of this include oxidative damage to DNA, proteins and cell membrane lipids, and altered cellular signal transductions as observed in many disorders such as diabetes, cardiovascular, autoimmune and chronic kidney diseases [5]

doi: 10.1016/j.bbagen.2013.07.009