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2) Abnormally elevated CD163+ macrophages drive excessive complex phagocytosis, leading to macrophage iron overload, LIP expansion, oxidative stress, and ferroptosis

Together we stand, apart we fall: how cell-to-cell contact/interplay provides resistance to ferroptosis

Braz J Biol 83:e270256

Lets look at some of the evidence behind this: Research-Backed Benefits of B12 for Neuropathy Studies have found that correcting a Vitamin B12 deficiency can alleviate neuropathy symptoms, particularly in patients with diabetic neuropathy and chemotherapy-induced neuropathy

Eur J Med Chem (2015) 97:5574
