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Table 1 The regulation of PPP enzymes in cancer cells
It inhibits the cysteine/glutamate antiporter system Xc-, thereby revoking cysteine import and thus reducing glutathione synthesis
For instance, inhibitors of glucose-6-phosphate dehydrogenase (G6PD) can be used to reduce NADPH levels in cancer cells, potentially enhancing the effectiveness of other treatments
Malabsorption Issues- Certain medical conditions, such as pernicious anaemia or gastrointestinal disorders, can interfere with the bodys ability to absorb B12 from food
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