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Although previous MMA mouse models recapitulate human disease, a model of MMA that has prolonged adult survival with the replication of the metabolic and clinical phenotypes seen in severe patients has not been developed

The drug should be discontinued if there are signs of the appearance or worsening of blood regurgitation, narrowing of the lumen of the clalans or thickening of the valve leaflets

Dosage couramment utilis : Utilisation gnrale : 500 mg 2 g par jour

Curr Neuropharmacol