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While the effects of structural diversity of CYP family proteins and interactions with different xenobiotic substrates should further be examined, the current results suggest that the interaction of drug-metabolizing CYPs with the haem-mediated dimer of PGRMC1 plays a crucial role in regulating their activities

Clinical investigations of Pycnogenol supplementation for twelve weeks in women aged 55 to 68 years found increased hyaluronic acid synthase mRNA levels by 44% and collagen type 1 mRNA levels by 40% in skin biopsies (25)

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BPC-157 seems to contribute to this protective function by helping in the fibroblast recruitment specialized cells that heal wounds

They call it a gerozyme because it increases with aging and slows the bodys ability to repair joint tissue