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autoimmune haemolytic anaemia, myasthenia gravis, idiopathic thrombocytopenic purpura, Sjogrens syndrome)[116]

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Dihydrofolate reductase (DHFR) controls the regeneration of BH2 to BH4, in which NAD(P)H is the principal cofactor that supplements BH4 but not BH2

Particularly common is a deficit in vitamin A, which is required for proper eye function and bone growth