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GI conditions, such as chronic pancreatitis, exocrine pancreatic insufficiency, and inflammatory bowel disease, can result in a decreased ability to absorb B12 in the GI tract, leading to a deficiency despite the dog eating a balanced diet

The speed at which a Vitamin B12 shot works can vary depending on several factors, including the individuals level of deficiency, overall health, and the presence of any underlying medical conditions

Cancer-Associated Fibroblasts Recruitment of cancer-associated fibroblasts CAFs are activated by growth factors released from tumor and inflammatory cells, including TGFb, PDGF, and FGF (169, 278, 279)

Dosing Frequency: Doses are typically repeated every one to two weeks depending on the animal's condition and how well