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Rare but serious events encompass provocation or exacerbation of seizures in susceptible individuals and hypersensitivity reactions ranging from urticaria to anaphylaxis
According to Valentini et al., acupuncture therapy may enhance microcirculation in patients suffering from peripheral artery disease (PAD) and diabetic foot syndrome (DFS) (125)

& Kurpisz, M

However, a large randomized trial found no improvement in semen quality or live birth with folic acid and zinc supplementation
