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Interestingly, -Ser-Lys- motif occurred in both sites of neurotrophin (within the 2 loop: - Ser 45 -Lys 46 -Gly 47 -Gln 48 -Lys 49 - and within the 4 loop: -Asp 93 - Ser 94 -Lys 95 -Lys 96 -), which are critical for BDNF/TrkB binding and activity and possess functional importance
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