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doi: 10.21873/cgp.20305 48 PaulMHemshekharMThusharaRMSundaramMSNaveenKumarSKNaveenSet al

Reduced glutathione is generally considered safe for skin whitening when used under medical supervision

While the transappendageal pathway, which utilizes appendages such as hair follicles, sweat ducts, and sebaceous glands, constitutes only about 0.1% of the skin surface area (though this percentage may be higher in specific regions such as the forehead) [22], its contribution to percutaneous transport is generally considered secondary

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