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This finding is consistent with organ selective distribution of the Na + -dependent GSH transporter in the brain and kidneys [53]

Less common complications include pancreatitis, which manifests as severe epigastric pain, and sensorineural hearing loss

Although global SIRT7 deficiency is known to cause systemic phenotypes such as cardiac hypertrophy and metabolic alterations, a VSMC-specific knockout model circumvented these systemic confounders, revealing a direct protective role of SIRT7 in vascular remodeling

PMID 25801590

Artificial intelligence: the Trait Dunion in different analysis approaches of autism spectrum disorder studies