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These are activated by leptin and secrete -melanocyte stimulating hormone (-MSH), which acts on second-order neurons present in the paraventricular area that express melanocortin 4 receptor(MC4R)

The following sections further explore cytokine-targeted therapeutic implications in respiratory diseases

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Furthermore, SARS-CoV-2-induced acute respiratory distress syndrome during pregnancy may result in fetal hypoxia, subsequently triggering tissue acidosis and excessive release of iron from hemoglobin and transferrin, thereby exacerbating lipid peroxidation and ultimately predisposing neonatal neural cells to ferroptosis ( Figure 4 4.1.4 Influenza viruses Influenza viruses, including influenza A virus (FLU A) and influenza B virus (FLU B), are single-stranded negative-sense RNA viruses classified under the Orthomyxoviridae family

Its activity depends on the presence of selenium, specifically in the form of selenocysteine located at the enzymes active site [80]