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Both should be protected from contamination by cleaning the vial stopper before each draw

Clinical guidance for intramuscular injections points to a 22 to 25 gauge needle, given at a 90-degree angle, with the length chosen so it reaches muscle without going too deep

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Signs of intramuscular injection include deeper, aching pain at the injection site, more soreness than usual lasting hours to days, bruising, faster onset of appetite suppression, and more intense initial side effects
