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Compounded semaglutide side effects The most common side effects of compounded semaglutide are: Nausea Abdominal discomfort Vomiting Diarrhea Constipation Rare and serious side effects of the medication include: Severe stomach problems Changes in vision (due to diabetic retinopathy) Hypersensitivity/allergic reaction Acute pancreatitis Gallbladder problems Hypoglycemia (low blood sugar levels) Increased risk of aspiration in anesthesia and sedation Mood and behavioral changes In rodents, semaglutide (the investigational product in clinical trials, which was later approved as Wegovy and Ozempic) increases the risk of thyroid cancers

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