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Description
Cagrilintide cant be codissolved with semaglutide so NVO will commercialize CagriSema in a dual-chamber injection device and thus sales potential is TBD, according to the Leerink note

TB-500 is more connected with cellular movement and repair-pathway studies

C D Differentiation
Same time daily maintains steady-state enzyme inhibition

This is because orforglipron is a small molecule absorbed through passive diffusion in the small intestine, rather than a peptide requiring the SNAC absorption enhancer and stomach-specific absorption conditions needed by Rybelsus
