invitrogen glutathione colorimetric detection kit 786-076 Absorbance is read at ~400 nm for GSH and ~356 nm for total mercaptens. Glutathione Assay Kit (Fluorometric)

Chunhong Yan (Augusta University) and Dr

[DOI] [PubMed] [Google Scholar] Wang F, Chen F, Cai Y, Zhang G, Wu F

Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, Tavernier G, Langin D, Spiegelman BM (2007) Transcriptional control of brown fat determination by PRDM16

It was concluded that small changes in the GSH/GSSG ratio is amplified to large effects on redox potential through the oxidation/reduction of cysteine residues within proteins, rather than changes in the GSH/GSSG ratio directly affecting the cellular redox potential [11]

For instance, drug exposure drives the phenotypic alterations of tumor cells, including dedifferentiation, EMT or trans-differentiation, marked by upregulated EMT-related transcriptional factors (TFs), including Zinc finger E-box binding homeobox 1 (ZEB1), ZEB2 and SLUG, that suppress pro-apoptotic proteins (BIM, BMF) and activate anti-apoptotic proteins (Bcl-xL, BCL- 2, MCL1) [38,39,40]