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According to a 2019 study, the rate at which vitamins lose their potency depends on the form of the supplement, the storage methods, and the date of manufacture

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Thus, it can be hypothesized that temporal changes in net proteolytic activity in human milk contribute to the FAA dynamics, although this is unlikely as levels of all major human milk proteases and anti-proteases decrease during lactation, along with levels of their substrates (50, 58)
Maquart et al

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