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Description
However, this difference in flux was primarily due to nutrient composition differences between plasma and cell culture medium, with supraphysiological glucose concentrations and a lack of appropriate TCA cycle fuels (e.g., lactate, shared metabolic demand that prioritizes rapid biosynthesis over efficient energyketone bodies, amino acids) in the latter (10, 11)
The other four genes GCLC , GHL , G6PD , and 6PGD showed reverse changes in both groups, being upregulated 1.874.13-fold after 2 days
Glutathione is a powerful antioxidant naturally produced by the body, playing a vital role in detoxification and cellular health

doi: 10.1002/ana.22162

Varese F, Smeets F, Drukker M, Lieverse R, Lataster T, Viechtbauer W, et al