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A large number of oncogenic proteins, including epidermal growth factor (EGFR), mitogen-activated protein kinase phosphatase-1, tumor necrosis factor receptor associated protein 1, phosphatase and tensin homolog (PTEN), p53, ras and src tyrosine kinase have been shown to be directly activated by S-nitrosation, which might have diverse functions in different stages of tumor progression [128]

mansoni juvenile worms, the LD 50 of PZQ (413 M) is inferior to that of inhibitors 1 - 5 (7.2 60% reduction in worm burden, a significantly higher efficacy than observed for treatment with PZQ in previous studies 13 , which had 0% reduction at 21 and 28 d.p.i

10.1021/acs.langmuir.6b00576 Langmuir 144 YilmazA