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Many contain hydrophobic regions that readily bind to plastic surfaces, pulling active peptide out of solution and depositing it on the container walls

We then gave these filtered media to gsh1 -cells and incubated them at 30.0 O C (green curves)

These findings, combined with evidence that systemic inflammation contributes to neurodegenerative and neuropsychiatric disorders, suggest that immune mechanisms are central to neural health and disease

Because the effect is systemic rather than purely local, the compound is theorized to act wherever tissue is trying to repair, not only at an injection site which is the stated rationale for systemic administration even in seemingly localized injuries

Technically yes, but the risk profile changes significantly