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[DOI] [PubMed] [Google Scholar] Sikiri P, Seiwerth S, Deskovi S, et al

The toxic effects of DOX administration observed in the current study are consistent with the findings of previous studies in which renal function parameters, including serum urea and creatinine, increased [35, 36]

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In addition to physical restriction of the potentially harmful substances, the BBB also plays multiple roles in maintaining homeostasis, 124,125 facilitating transport of the essential molecules, 126 regulating inflammation 127,128 and so forth