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Trends Cancer 10 (1), 3851

11 , e201700267 (2018)

Blocking B7 in this patient would prevent the crucial CD28-mediated costimulatory signal, thereby suppressing rather than enhancing the anti-tumor immune response needed to treat his metastatic melanoma

Carnitine deficiency impairs the mitochondrial -oxidation of FAs, leading to acute metabolic decompensation, elevated aminotransferase, and hepatic encephalopathy similar to NAFLD (75)

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