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Factor 3: Balance convenience against precision

In a typical rate case, which is how utilities ask regulators to let them change customer rates, individuals and organizations can file to participate in negotiations

Secondary endpoints also improved significantly, including body mass index reduction and favorable changes in cardiometabolic risk factors such as waist circumference, blood pressure, lipid profiles, glycemic control, and markers of inflammation

doi: 10.1016/0006-2952(93)90072-5

Genomic sections displaying sequence conservation over time within a single viral species or evolutionary conservation between members of the coronavirus family despite high mutation rates are indicative of essential regions of the viral genome that are functionally constrained, such as the fusion peptide within the spike S2 region [68, 69]