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Information from the Specialized Literature (GHK-Cu Substance) Given that Copper Tripeptide-1 is a substance that has been extensively investigated in dermatological and trichological research, independent studies published in recent years have highlighted its remarkable potential: Modulation of Growth Factors: Recent studies indicate that GHK-Cu can influence the expression of growth factors in human dermal papilla cells, which are essential for follicle vitality

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The peptide activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in a dose-dependent manner, leading to nuclear translocation and activation of transcription factors including c-Fos, c-Jun, and early growth response-1 (Egr-1) that drive expression of genes involved in cell growth, migration, and angiogenesis