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Description
e-Pub 2014

Traditional treatments like NSAIDs and corticosteroids provide temporary relief but come with significant drawbacks

A number of US studies demonstrated poor compliance with CHB practice guidelines among treating physicians, in particular regarding regular monitoring of CHB status (using markers such as HBV DNA and alanine aminotransferase [ALT]), performance of liver biopsy to guide treatment decisions, treatment initiation among patients considered eligible for anti-HBV therapy, use of recommended agents, and HCC surveillance 1416
Common cycles are 30 days on and 14 days off, or 8 weeks on and 4 weeks off for intensive use

They are also developing new treatment protocols that integrate MTH1 inhibitors with different therapeutic methods
