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Approaches using radiolabeled anti-CD38 conjugates have resulted in high tumor-to-normal organ ratios and reduced toxicity and sdAb#2F8 labeled with therapeutic radionuclides confirmed its potential as theranostic tools (Fig

CD38 is also important in acute lymphoblastic leukemia (ALL), an aggressive cancer of B or T lymphoblasts characterized by uncontrolled proliferation of immature lymphocytes [25]