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While many people get enough vitamin B12 naturally from their diets, vegetarians and vegans will often need a supplement because they eat little or no animal protein

For example, using peptides together with medicines metabolized by cytochrome P450 can lead to increased levels of these medicines in the blood, which may raise the risk of side effects

Multi-week culture studies examining collagen, elastin, and proteoglycan gene expression often require repeat dosing of cultures across several passages, which draws down stock material more quickly than a single-endpoint assay

Working through the calculation carefully prevents the dosing errors that compromise research validity

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