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Considerable genetic studies in SLE patients and animal models implicate the role of oxidative stress in the pathogenesis of SLE

Bei unsachgemer Dosierung kann es zu einer berreaktion mit verstrkter Tagesmdigkeit kommen, weshalb eine individuelle Dosisanpassung wichtig ist

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25 The thiol group in NAC reduces the activity of elastase, decreases plasma myeloperoxidase (MPO) and the capacity of elastic protease, as well as decreasing the production of lactoferrin and eosinophil cationic protein in BALF, neutrophil chemoattractant activity 26 and neutrophil chemoattractant release in sputum of COPD patients
