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Typically sourced from meat in our diets, B-12 might not be adequately absorbed due to dietary restrictions or health concerns, necessitating a natural supplement such as a B-12 shot

During adulthood, serum B12 concentrations tend to decline with age, especially in the elderly (Wahlin et al., 2002), probably arising from the gradual decrease in both gastric acidity and intrinsic factor production that occurs with aging (Asselt et al., 1998

Some genetic diseases that involve defects of transcobalamin, methylmalonyl CoA mutase, or enzymes in the pathway of cobalamin adenosylation, may also result in vitamin B12 deficiency (IOM, 2000)

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Which is exactly why it deserves a clear, grounded explanation