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10.1038/s41598-021-87678-x Sci Rep

The facial skin develops uneven melanin distribution patterns because of B12 deficiency, which causes these spots to appear
Diabetes 64 , 916925 (2015)

They are not a substitute for appropriate treatments

Differences between pre- and posttreatment measurements in concentrations of GABA, Gln, Glu, GSH, and NAA were compared using a paired t test
