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Animal and in vitro experiments have further verified its barrier repair effect: Butyrate can promote proliferation and mucin secretion of intestinal epithelial cells (IPECs, Caco-2, HT-29), enhance the expression of tight-junction proteins (ZO-1, Claudin-1, Claudin-2), and maintain colonic mucosal integrity (7682)

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These data unravel a mechanism that explains the transition from asymptomatic autoimmunity to inflammatory disease

5c) among the groups, indicating that there were no significant differences in exploratory or locomotor activity
GH-axis manipulation can complicate insulin sensitivity and fluid balance in some individuals
