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AOD9604 has a generally recognized as safe (GRAS) status for supplement use

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2018 867 (American Medical Informatics Association, 2018)
HMG-CoA reductase inhibitors (statins) to reduce cellular production of cholesterol Medications to lower cholesterol absorption from the intestine (eg bile acid sequestrants like colesevelam) PCSK9 inhibitors, which allow LDL to bond to its receptors and be removed from the blood For people who require additional LDL lowering, the new drug bempedoic acid may be recommended in addition to statin therapy