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MDA concentration was calculated using a standard curve prepared from 1,1,3,3-tetramethoxypropane and expressed as nmol per milligram of protein

The results of an in vivo study demonstrated that the apoptosis rate of RSC96 cells treated with HG for 48 h was increased by 9.72-fold, confirming that high glucose also elevated the mitochondrial pathway apoptosis-related Bax/Bcl-2 and cleaved caspase-9/caspase-9 ratios, and suggested that knockdown of histone deacetylase (HDAC1) could effectively inhibit HG-promoted mitochondrial apoptosis (42)

It functions as a powerful antioxidant, shielding the skin from cell damage

Spine 28(2): 134-139, 2003

Braz J Cardiovasc Surg