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doi: 10.1016/j.neuropharm.2007.05.016

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Long-term administration (12 months) of L-carnitine (2 g/day) to hemodialyzed patients resulted in increased serum and muscle carnitine levels, and selective type 1 fiber hypertrophy [86] and similar results have been obtained in uremic patients following 24 weeks administration of the same dose [87] but the functional significance of such changes remains to be elucidated

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