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Based on the assumption that -Syn dimerization on the membrane surface is crucial for the oligomerization of -Syn [317,318], they performed a molecular dynamics analysis that revealed a dimerization-responsible pharmacophore region located on residues 96102 at the C -terminal domain

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Instead of a simple side-chain modification, cysteine residues can form disulfide bonds with each other

[DOI] [PubMed] [Google Scholar] 118.Corcoran C., Perrin M., Harlap S., Deutsch L., Fennig S., Manor O., Nahon D., Kimhy D., Malaspina D., Susser E

(24) Leonard, B