side effects from vitamin b12 injections in humans Are Shots Safe? Royal Palm Beach Medical Group Why do I feel worse

The net physiological effect of Glycine Injection depends on dose and route of administration: lower doses primarily supplement normal metabolic needs, whereas high doses (especially if given rapidly) may cross the blood-brain barrier and significantly alter neurotransmitter dynamics

Inadequate dietary intake

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Vegans may need B12 supplements or consume B12-fortified foods

In some cases, individuals with low B12 may also develop a slight yellowing of the skin or eyes, a condition known as jaundice