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Since every person is different, the optimal monitoring interval may vary

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Therefore, regardless of the presence of neurological symptoms, SCD should be suspected in patients with skin hyperpigmentation, as the neurological manifestations can be a late finding [2]

Protein concentration was determined using a DC Protein Assay Kit, (Bio-Rad, United States)

If signs of infection (e.g., pus, warmth, significant redness) develop, seek medical attention