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PRMT5 inhibitors GSK591 and ly-283 caused a broad inhibition of transcriptome splicing in GBM cells, particularly affecting the products of cell cycle genes and prolonged survival in the PDX mouse model

Published 2017 Oct 22

Theres even a modified version, CJC 1295 DAC, with an even longer half-life
BrainMax Liposomal Glutathione was the subject of a randomized, controlled study
