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Its mechanism of action appears to be linked to the activation of the PINK1/Parkin pathway, promoting mitophagy and attenuating apoptotic processes

Hyperhomocysteinemia results from an inhibition of the remethylation pathway or from an inhibition or a saturation of the transsulfuration pathway of homocysteine metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Gould L, Abadir P, Brem H, et al

Quinlan et al., 2013), complex I and complex III (Venditti et al., 2013) have been shown to be the most important sources of mitochondrial superoxide generation, although significant production of ROS in complex II has recently also been reported (Quinlan et al., 2012)

This can manifest in various neurological symptoms, including cognitive issues and increased sensitivity to stress