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Description
Rotate injection sites (abdomen, thighs, upper arms) to reduce local irritation and prevent lipohypertrophy [8]
In all cases, cessation of smoking is essential
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Minich and Brown, 2019
Causes remain somewhat elusive, but the condition is linked to a malfunction of the autonomic nervous system
Patients with certain variants may show higher baseline inflammatory markers or slower adaptation to rapid metabolic change
