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Surprisingly, all recombinant strains had a lower [reduced glutathione]:[oxidized glutathione] ratio (ranging from 3267) than the wild type strain (88), suggesting a more oxidized intracellular environment in the engineered strains

Studies demonstrate strong effects in IBD models, psoriasis, and neuroinflammation

Psychological stress and mitochondria: a conceptual framework

In this line, GSTA1, GSTM1 and GSTP1 participate in conjugation of tobacco smoke metabolites with glutathione, thus enhancing their excretion in urine, while due to strong peroxidase activity they are among key components in cellular defense against free radical damage 9,32,33

doi: 10.1007/s00403-018-1827-7 83