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The most commonly reported side effects are typically mild and transient, occasionally including minor gastrointestinal upset, nausea, or heartburn, particularly if the supplements are taken on an empty stomach or in excessively high doses all at once

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This enzymes job is to help break down a substance called isovaleryl-CoA. It is made in the body when the amino acid leucineThis is one of 20 amino acids that make up protein