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Description
Numerous metabolites produced by cancer cells, including itaconate, L-kynurenine, lactic acid, and hyaluronic acid, have been demonstrated to activate Nrf2 and play a significant role in regulating the TIME and tumor-TAMs interaction

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It provides protection for sperm DNA against OS damage in a mechanism that is not very well-established

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demonstrated that IGF-1 overexpression in differentiated L6E9 cells resulted in pronounced myotube hypertrophy and myogenin induction [120]
